When Dr. Joy Gilbert is fired from a lucrative position she hates in the city, she returns to her small hometown to find her former fiance single, her once vivacious mother struggling financially and physically, and Tressa, the 15–year–old daughter of the boss who just fired her, popping out of the back door of her car. Tressa refuses to return to the city, where her divorced parents struggle emotionally over the death of their son.

When Dr. Zack Tyler sees Joy walk into the ER with the daughter of the man who lured Joy away from him, he’s hesitant, though he’s overjoyed to see her again. Out of compassion, he hires her in the ER so she can support herself and her mother, and their relationship blooms. Meanwhile, Tressa has blackouts that grow increasingly bad. Joy and Zack rediscover their love for one another as they discover what caused the breakup. Together they work to save Tressa and uncover a rare genetic defect, a mystery that has ravaged decades of Tressa’s family line.